Faculty and staff directory

Janina P. Lewis, Ph.D.

Janina P. Lewis, Ph.D.

Associate professor

Philips Institute of Oral and Craniofacial Molecular Biology
Wood Memorial Building
521 North 11th Street
Box 980566
Richmond, Virginia 23298-0566
Phone: (804) 628-7014
Fax: (804) 828-0150
Email: jplewis@vcu.edu


Education

  • Ph.D. in Microbiology and Immunology, Virginia Commonwealth University, 1997
  • M.S. in Biology, The University of Gdansk, Poland, 1990

Research interests

  • Virulence of oral gram-negative bacteria implicated in development and progression of periodontal disease

Publications

He J, Anaya C, He J, Miyazaki H, and Lewis JP. 2009. Identification and characterization of Prevotella intermedia 17 fibrinogen binding protein (manuscript in preparation).

Iyer D, Anaya-Bergman C, Jones K, Yanamandra S, Miyazaki H, and Lewis JP. Identification and characterization of internalin-like protein from Prevotella intermedia 17. Manuscript in review.

Anaya C, He J, Miyazaki H, Yeudall WA, and Lewis JP. 2009. The ferrous iron uptake protein FeoB1 is dispensable for oxidative stress protection and survival of Porphyromonas gingivalis in host cells. Manuscript in revision.

Maeda K, Tribble GD, Tucker CM, Anaya C, Shizukuishi S, Lewis JP, Demuth DR, and Lamont RJ. 2008. A Porphyromonas gingivalis tyrosine phosphatase is a multifunctional regulator of virulence attributes. Mol Microbiol. 69:1153-1164.

Zhang P, Lewis JP, Michalek SM, and Katz J. 2007. "Role of CD80 and CD86 in Host Immune Responses to the Recombinant Hemagglutinin Domain of Porphyromonas gingivalis Gingipain and in the Adjuvanticity of Cholera Toxin B and Monophosphoryl Lipid A". Vaccine 25: 6201-6210.

Anaya C, Church N, and Lewis JP. 2007. Detection and Identification of Bacterial Cell Surface Proteins by Fluorescent Labeling. PROTEOMICS 7:215-219.

Yu F, Iyer D, Anaya C, and Lewis JP. 2006. Identification and characterization of a cell surface protein of Prevotella intermedia 17 with broad-spectrum binding activity for extracellular matrix proteins. PROTEOMICS 6:6023-6032.

Lewis JP, Plata K, Yu F, Rosato A, and Anaya C. 2006. Transcriptional organization, regulation and role of the Porphyromonas gingivalis W83 hemin uptake (hmu) locus. Microbiology 152:3367-3382.

Yu F, Anaya C, and Lewis JP. 2006. Outer membrane proteome of Prevotella intermedia 17: Identification of thioredoxin and iron-repressible hemin uptake loci. PROTEOMICS 7:403-412.

He J, Miyazaki H, Anaya C, Yu F, Yeudall A, and Lewis JP. 2006. Role of Porphyromonas gingivalis FeoB in metal uptake and oxidative stress protection. Infection and Immunity 74:4214-4223.

Zhang P, Yang QB, Balkovetz DF, Lewis JP, Clements JD, Michalek SM, and Katz J. 2005. Effectiveness of the B subunit of cholera toxin in potentiating immune responses to the recombinant hemagglutinin/adhesin domain of the gingipain Kgp from Porphyromonas gingivalis. Vaccine 23:4734-4744.

Califano JV, Chou D, Lewis JP, Rogers JD, Best AM, and Schenkein H. 2004. Antibody reactive with Porphyromonas gingivalis hemagglutinin in chronic and generalized aggressive periodontitis. J Periodontal Res. 39:263-268.